台灣外科醫學會雜誌

中文 | ENG

	第58卷第1期 2025-1 Ensuring authorship qualification in clinical research articles: A focus on surgical therapy studies
.........................
	第58卷第1期 2025-1 Estimated risk for transfusion of monkeypox contaminated perioperative blood transfusion: A call to action for stronger regulations and testing protocols
.........................
	第58卷第1期 2025-1 Insights into traumatic and crisis surgery: Implications of data analysis in conflict zones
.........................
	第58卷第1期 2025-1 Tongue peeling as an adverse reaction with use of micronized purified flavonoid: A case report
.........................
	第58卷第1期 2025-1 Pilonidal sinus of scrotum: A rare clinical entity
.........................
	第58卷第1期 2025-1 Incidental autopsy finding of retiform hemangioendothelioma of the spleen
.........................
	第58卷第1期 2025-1 Retroperitoneal laparoscopy for hydronephrosis due to multiple fibroepithelial polyps: A case series
.........................
	第58卷第1期 2025-1 Case reports of type 1 cystic biliary atresia—A rare variant of biliary atresia alongwith reviewof literature
.........................
	第58卷第1期 2025-1 The predictors of intraoperative surgical expenses in liver resection for hepatocellular carcinoma
.........................
	第58卷第1期 2025-1 Intracorporeal anastomosis versus extracorporeal anastomosis following laparoscopic right hemicolectomy: Surgical outcomes of a single-center observational study
.........................
	第58卷第1期 2025-1 Quality of life and spiritual health in motorcycle accident survivors: An analysis using the SF-36 Questionnaire and Spiritual Scale
.........................
	第58卷第1期 2025-1 Plastin 3 expression in circulating tumor cells as a predictor of cancer status in patients with prostate cancer
.........................
	第57卷第6期 2024-11 Emerging robot-guided techniques in endodontic microsurgery
.........................
	第57卷第6期 2024-11 Management of subcapsular hematoma after living donor liver transplant
.........................
	第57卷第6期 2024-11 Urethral pseudodiverticulum with left-sided nonfunctioning kidney: Case report
.........................
	第57卷第6期 2024-11 Strategy to minimize surgical defect of dermatofi brosarcoma protuberans
.........................
	第57卷第6期 2024-11 Rapunzel syndrome—An uncommon disease with varied common presentations
.........................
	第57卷第6期 2024-11 Minimally invasive approaches to management of acute necrotizing pancreatitis
.........................
	第57卷第6期 2024-11 Innovative surgical technique: Addressing ethical concerns
.........................
	第57卷第6期 2024-11 Emergency surgery and HIV screening, clinical or universal scenarios?
.........................

登入帳號才能閱讀全文

篇名	The capabilities of benzoporphrin: In vivo study of canine malignant melanomas with photodynamis tgerapy
作者	Cheng-Jen Chang, Chen-Nun Chang, Tsann-Lang Hwang
卷期/出版年月	35卷4期 (2002/8)
頁次	166-172
摘要	Human malignant melanomas are a kind of commenly occurring neoplasm with a clinical of recurrence after surgical removal. This preliminary animal study seeks to evalute the effect of benzoporphyrin derivative (BPD) in photodynamic therapy (PDT) for spontaneously arising melanoma in canines. The dogs with spontaneously occurring melanomas were treated with PDT using BPD as the photosensitizer. BPD was injected intravenously at a dose of 1 mg/kg. Six hours later the treatment of PDT with 690 nm light was taken. Some larger tumors (>1.5 cm deep) were surgically debulked prior to PDT. No sighificant systemic toxicity or skin photosensitization was observed. PDT with BPD led to a complete reponse in 70% (7 of 10) of these cases. 20% (2 of 10) had a partial response, and 10% (2 of 10) no response (<50% reduction of tumor size). BPD-PDT appears to have advantages in the treatment of canine melanomas, and systemic toxicity is almost nonexistent. Further studies of the long results are necessary before BPD-PDT canbe used in humans.
關鍵詞	Melanoma, photosensitizer, photodynamic therapy
分類	Original Article