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第57卷 第1期 2024-1
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Reflections on the association between cholecystectomy, cholelithiasis, and colorectal cancer

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Early decompressive surgery within 72 hours of admission maintains financial advantages for patients with spinal epidural abscess, as evidenced by a retrospective study involving 130 cases

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篇名 Prospective randomized control study comparing gauze‑based with foam‑based negative pressure wound therapy for the stage 4 pressure injuries
作者 Chiun‑Sheng Chen, Chao‑Chin Yu
卷期/出版年月 51卷6期 (2018/12)
頁次 223-227
摘要 Background: Negative pressure wound therapy (NPWT) has been used to accelerate the formation of granulation tissue and to promote wound closure in the treatment of difficult‑to‑heal wounds. This study compared the effectiveness between gauze‑ and foam‑based NPWT for stage 4 pressure injuries. Materials and Methods: A total of 38 patients with 48 wounds of stage 4 pressure injuries were recruited and randomly divided into gauze‑based and foam‑based groups. After initial debridement therapy, gauze‑based and foam‑based fillers were used, and clinical observations were recorded when dressings were changed, twice a week for 3 weeks. The system was connected to a 1‑bottle water‑seal chest drainage system and standard wall suction at 125 mmHg negative pressure. The percentages of wound area reduction (PWAR), the scores of Pressure Ulcer Scale for Healing (PUSH) tool and the scores of Bates‑Jensen wound assessment tool (BWAT) were used to evaluate wound healing activity. Results: Both groups showed significant changing trends in the wound assessments of PWAR, PUSH, and BWAT during follow‑up. However, the area of healing at each clinical observation was consistently greater in the foam group than in the gauze group during the follow‑up period, while the PUSH score was consistently greater in the gauze group than that in the foam group. The declining trends of BWAT were alike in both groups. Conclusion: Gauze‑based therapy is noninferior to foam‑based therapy with respect to PWAR, PUSH, and BWAT for stage 4 pressure injuries.
關鍵詞 Clinical trial, gauze and foam fillers, negative pressure wound therapy, pressure injury
分類 Original Article

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