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第58卷 第3期 2025-5
Elevating the standards of scientific editing in clinical surgery: Learning from editorial and journal role models

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第58卷 第3期 2025-5
Improving online physician evaluations for surgeons using sentiment analysis and alternative perspectives

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第58卷 第3期 2025-5
Ensuring ethical and qualified authorship: The key to trustworthiness in clinical surgery journal

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第58卷 第3期 2025-5
Artificial intelligence for academic purpose in clinic surgery: ChatGPT, Turnitin, and false positive

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第58卷 第3期 2025-5
COVID-19, COVID-19 vaccination, risk of cardiac myxoma in view of clinical surgery

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第58卷 第3期 2025-5
Eggplant deformity in penile fracture

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第58卷 第3期 2025-5
Splenectomy for Klippel-Trenaunay syndrome: Systematic review and case series

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第58卷 第3期 2025-5
Comments on “Risk factors for spinal cord injury without radiographic abnormality in trauma cases at a single trauma center”

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第58卷 第3期 2025-5
Impact of fluorescence-guided surgery on splenic preservation: A case of splenic hydatidosis

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第58卷 第3期 2025-5
Adult pancreatoblastoma presentingwith obstructive jaundice: A case report and literature review

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第58卷 第3期 2025-5
Pilonidal disease management in young adults: A retrospective analysis of practices in a single tertiary center in Bahrain

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第58卷 第3期 2025-5
Long-term comparative outcomes in patients undergoing transcatheter aortic valve implantation with self-expanding valves versus balloon-expandable valves: A retrospective observational study

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第58卷 第3期 2025-5
Comparative study between the effectiveness of Amnion-CollaGee (Collagen-Gelatin-Elastin) as a biological product wound dressing and conventional dressing on the donor site of the split-thickness skin graft in animals model (rats)

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第58卷 第3期 2025-5
Enhancing mortality Probability Model II predictive accuracy with the lethal triad in intensive care unit trauma patients: A retrospective study

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第58卷 第3期 2025-5
Dr. Shao-Wei Chen's contribution to analysis of outcomes of patients undergoing cardiac surgery and aortic disease: Big data analytics

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第58卷 第2期 2025-3
Predatory publisher and low standard journal: An emerging problem in clinical surgery field

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第58卷 第2期 2025-3
Conflict of interest in clinical surgery: Contemporary concern in digital era

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第58卷 第2期 2025-3
Postpublication redecision and pitfalls of inadequate standards in scientific surgical journals: Important consideration in academic publication

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第58卷 第2期 2025-3
Spontaneous bilateral basal ganglia hemorrhage

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第58卷 第2期 2025-3
Academic characterization of the Formosan Journal of Surgery: A five-year bibliometric analysis

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篇名 Multiple primary malignant neoplasms: Results from a 5‑year retrospective analysis in a Metropolitan Hospital
作者 Chih‑Cheng Sun, Chi‑Chang Chang
卷期/出版年月 50卷6期 (2017/12)
頁次 209-214
摘要 Background: The high effectiveness of cancer screening and therapies resulted in the increased diagnosis of multiple primary malignancies (MPMNs) in Taiwan. The aim of the present study was to investigate the clinical data of patients and to determine the frequency and clinical features of MPMNs. Methods: Between January 2010 and December 2014, a total of 2518 patients were screened and obtained retrospectively from the Tumor Registry Center of a metropolitan hospital. We quantified the clinical features and the most common cancer pairs of MPMNs using statistical and epidemiological indicators. Results: Two hundred and eleven patients with MPMNs were evaluated. The median age at initial cancer diagnosis was 63 years old (range 12–100 years). The median age of diagnosis of secondary cancer was 67 years old (range 35–95 years). The median time between initial and secondary cancer diagnoses was 5 months (range 0–57.1). The overall incidence of MPMNs was 8.38%, and the male: female ratio was 2.01:1. The most frequent types of cancer at secondary diagnosis were digestive (79 patients, 3.05%), breast (22 patients, 0.87%), liver (22 patients, 0.87%), head-neck (18 patients, 0.71%), and bladder cancer (14 patients, 0.56%). In women, the most frequent types of cancer at secondary diagnosis were digestive (25 cases, 2.21%), breast (22 cases, 1.95%), liver (11 cases, 0.97%), lung (8 cases, 0.71%), and gynecologic cancer (7 cases, 0.62%). In men, the most frequent types of cancer at secondary diagnosis were digestive (54 cases, 3.89%), head-neck (16 cases, 1.15%), liver (11 cases, 0.79%), bladder (10 cases, 0.72%), and prostate cancer (10 cases, 0.72%). The most common cancer pairs in males were digestive/digestive (22 cases, 1.59%), headneck/head-neck (4 cases, 0.29%), lung/digestive (3 cases, 0.22%), and prostate/bladder (3 cases, 0.22%). In addition, tobacco smoking, alcohol consumption, and betel-chewing were observed to be important risk factors for the development of MPMNs. Conclusion: Indeed, the cancer registries can help us understand the disease better and use our resources to the best effect in prevention and treatment of MPMNs. In the present study, we discovered that patients with MPMNs tend to be older than those with a single primary malignant neoplasm. In conclusion, the clinical features and the most common cancer pairs of MPMNs are demonstrated in the present study. Based on these data, further analysis of the relationship between them is worthwhile.
關鍵詞 Multiple primary malignant neoplasms, retrospective analysis, tumor registry center
分類 Original article

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