中文 | ENG

第51卷 第5期 2018-10
Fishbone‑related liver abscess

.........................

第51卷 第5期 2018-10
Chest wall pleomorphic liposarcoma combined with lung extraskeletal osteosarcoma

.........................

第51卷 第5期 2018-10
Burkitt’s Lymphoma Presenting as Ovarian Mass and Ileocecal Intussusception in an Adult

.........................

第51卷 第5期 2018-10
Surgical versus conservative management for suppurative intramural esophageal dissection

.........................

第51卷 第5期 2018-10
Small cell carcinoma of upper urinary tract: A pooled analysis of survival

.........................

第51卷 第5期 2018-10
Improvement of satisfaction in burn patients receiving adjuvant hyperbaric oxygen therapy

.........................

第51卷 第5期 2018-10
Treatment results in the same surgery method of the high cervical spinal schwannoma

.........................

第51卷 第5期 2018-10
Chronic periodontal disease correlated with sezual function in young males

.........................

第51卷 第4期 2018-8
Idiopathic isolated omental panniculitis presenting with intestinal obstruction

.........................

第51卷 第4期 2018-8
Heterotopic subserosal pancreatic tissue in jejunum

.........................

第51卷 第4期 2018-8
Surgical intervention of a giant gastric gastrointestinal stromal tumor following neoadjuvant therapy with imatinib

.........................

第51卷 第4期 2018-8
Surgical treatment for duodeno‑reno‑cutaneous fistula

.........................

第51卷 第4期 2018-8
Laparoscopic liver resection for polycystic liver disease

.........................

第51卷 第4期 2018-8
The result of emergency cardiac intervention in resuscitated out‑of‑hospital cardiac arrest patients

.........................

第51卷 第4期 2018-8
The use of perforator flaps for the reconstruction of sacral defects: Ten-year experience

.........................

第51卷 第4期 2018-8
Chloroquine induces lysosomal membrane permeabilitymediated cell death in bladder cancer cells

.........................

第51卷 第3期 2018-6
Emphysematous gastritis after radical subtotal gastrectomy for advanced gastric cancer

.........................

第51卷 第3期 2018-6
Primary cervical spine melanoma

.........................

第51卷 第3期 2018-6
Jejunostomy tube-induced intussusception

.........................

第51卷 第3期 2018-6
Adult‑onset neurocutaneous melanosis with Dandy–Walker malformation

.........................
登入帳號才能閱讀全文
 
篇名 Multiple primary malignant neoplasms: Results from a 5‑year retrospective analysis in a Metropolitan Hospital
作者 Chih‑Cheng Sun, Chi‑Chang Chang
卷期/出版年月 50卷6期 (2017/12)
頁次 209-214
摘要 Background: The high effectiveness of cancer screening and therapies resulted in the increased diagnosis of multiple primary malignancies (MPMNs) in Taiwan. The aim of the present study was to investigate the clinical data of patients and to determine the frequency and clinical features of MPMNs. Methods: Between January 2010 and December 2014, a total of 2518 patients were screened and obtained retrospectively from the Tumor Registry Center of a metropolitan hospital. We quantified the clinical features and the most common cancer pairs of MPMNs using statistical and epidemiological indicators. Results: Two hundred and eleven patients with MPMNs were evaluated. The median age at initial cancer diagnosis was 63 years old (range 12–100 years). The median age of diagnosis of secondary cancer was 67 years old (range 35–95 years). The median time between initial and secondary cancer diagnoses was 5 months (range 0–57.1). The overall incidence of MPMNs was 8.38%, and the male: female ratio was 2.01:1. The most frequent types of cancer at secondary diagnosis were digestive (79 patients, 3.05%), breast (22 patients, 0.87%), liver (22 patients, 0.87%), head-neck (18 patients, 0.71%), and bladder cancer (14 patients, 0.56%). In women, the most frequent types of cancer at secondary diagnosis were digestive (25 cases, 2.21%), breast (22 cases, 1.95%), liver (11 cases, 0.97%), lung (8 cases, 0.71%), and gynecologic cancer (7 cases, 0.62%). In men, the most frequent types of cancer at secondary diagnosis were digestive (54 cases, 3.89%), head-neck (16 cases, 1.15%), liver (11 cases, 0.79%), bladder (10 cases, 0.72%), and prostate cancer (10 cases, 0.72%). The most common cancer pairs in males were digestive/digestive (22 cases, 1.59%), headneck/head-neck (4 cases, 0.29%), lung/digestive (3 cases, 0.22%), and prostate/bladder (3 cases, 0.22%). In addition, tobacco smoking, alcohol consumption, and betel-chewing were observed to be important risk factors for the development of MPMNs. Conclusion: Indeed, the cancer registries can help us understand the disease better and use our resources to the best effect in prevention and treatment of MPMNs. In the present study, we discovered that patients with MPMNs tend to be older than those with a single primary malignant neoplasm. In conclusion, the clinical features and the most common cancer pairs of MPMNs are demonstrated in the present study. Based on these data, further analysis of the relationship between them is worthwhile.
關鍵詞 Multiple primary malignant neoplasms, retrospective analysis, tumor registry center
分類 Original article

台灣外科醫學會雜誌 © 2006 Taiwan Surgical Association All Rights Reserved
會 址:台北市南京東路五段 31 號 3 樓
電 話:(02) 2769-7845 傳 真:(02) 2746-7149 Email: journal@24drs.com