|
|
第57卷 第2期 2024-3
Necrotizing fasciitis resulted from foreign body ingestion and intestinal perforation in an incisional hernia: Report of a case |
| ......................... |
|
第57卷 第2期 2024-3
Application of artificial intelligence in endodontic microsurgery |
| ......................... |
|
第57卷 第2期 2024-3
A rare case of cerebral metastasis of malignant peripheral nerve sheath tumor in a patient with neurofibromatosis type 1 |
| ......................... |
|
第57卷 第2期 2024-3
Ethic in commenting and clinical surgery journal publication: Emerging issue in the era of social media—A story from “Beall” to “Jaime” and independent researcher |
| ......................... |
|
第57卷 第2期 2024-3
Ophidascaris robertsi, the new emerging human parasite and neurosurgery |
| ......................... |
|
第57卷 第2期 2024-3
Tetanus toxoid IgG, usefulness in clinical surgery, and diagnostic property limitation |
| ......................... |
|
第57卷 第2期 2024-3
Deaths among surgeons while on duty: An important issue in surgery and occupational medicine that should not be disregarded |
| ......................... |
|
第57卷 第2期 2024-3
ChatGPT and its use in clinical surgery: A comment on its pro and con |
| ......................... |
|
第57卷 第2期 2024-3
Isolated spinal neurocysticercosis and pseudotumor cerebri: Tropical problem to be noted |
| ......................... |
|
第57卷 第2期 2024-3
Management of massive hemothorax resulting from traumatic diaphragm rupture with kidney avulsion injury by combined anterior thoracoabdominal approaches |
| ......................... |
|
第57卷 第2期 2024-3
Laparoscopic partial splenectomy for sclerosing angiomatoid nodular transformation: A case report and literature review |
| ......................... |
|
第57卷 第2期 2024-3
Using three-dimensional versus two-dimensional laparoscopy in sleeve gastrectomy: A case matched comparison |
| ......................... |
|
第57卷 第2期 2024-3
Effectiveness of placing prophylactic mesh with the Sugarbaker technique via laparoscopic abdominoperineal resection for rectal cancer: 1-year results |
| ......................... |
|
第57卷 第2期 2024-3
Nylon cable ties–assisted delay primary closure of fasciotomy wound in patients of forearm compartment syndrome |
| ......................... |
|
第57卷 第2期 2024-3
Prefabricated venous fl ap, an advanced free venous fl ap for distant transfer: An experimental rat study |
| ......................... |
|
第57卷 第1期 2024-1
Isolated lower leg monoplegia due to traumatic intraparenchymal hemorrhage |
| ......................... |
|
第57卷 第1期 2024-1
Reflections on the association between cholecystectomy, cholelithiasis, and colorectal cancer |
| ......................... |
|
第57卷 第1期 2024-1
Molluscum contagiosum, false positive, and incidence: Concern in surgery |
| ......................... |
|
第57卷 第1期 2024-1
New form of COVID-19 vaccine: A new advanced technology for fighting the remained problem |
| ......................... |
|
第57卷 第1期 2024-1
COVID-19 vaccination, acute appendicitis, interrelationship, and jointed probability: A concern |
| ......................... |
|
 |
| 篇名 |
Distant Failure Patterns of Resected Stage I Non-small Cell Lung Cancer: a Long-term Follow-up |
| 作者 |
Jung-Jyh Hung, Yu-Chung Wu, Min-Hsiung Huang,Biing-Shiung Huang, Liang-Shun Wang, Wen-Hu Hsu |
| 卷期/出版年月 |
39卷5期 (2006/10) |
| 頁次 |
227-235 |
| 摘要 |
Objective: Resection is the best treatment for patients with Stage I non-small cell
lung cancer (NSCLC). Distant metastasis is the most frequent cause of treatment
failure and cause of death in NSCLC. The goal of this study was to evaluate the
clinicopathologic characteristics, pattern of distant failure, disease-free time and
survival in patients with resected Stage I NSCLC.
Methods: We retrospectively reviewed the clinicopathologic characteristics of 155
patients of resected Stage I NSCLC with distant failure in Taipei Veterans General
Hospital between 1980 and 2000. Disease-free time, survival, and their predictors
were analyzed.
Results: Patients were followed up for 20.5 months (mean, 25.4 19.5 months).
Distant failure occurred at 11.5 months (median, 95% CI: 9.8 to 13.6 months). The
disease-free rate and survival at 2 and 5 years were 12.9% and 1.3%, and, 43.2% and
6.5%, respectively. The sites of distant failure were bone in 52 (33.5%), lung to lung
in 39 (25.2%), brain in 37 (23.9%) and liver in 17 (11.0%). A second site of distant
failure was noted in 35 of 155 patients (22.6%): bone in 13 (37.1%) and lung to lung
in 8 (22.9%). Multivariate analysis showed that tumor size and histological type had
significant impact on disease-free survival (P=0.003, 0.003), and tumor size,
histological type and first site of distant failure had significant impact on overall
survival (P=0.034, <0.001, 0.009). Patients with squamous cell carcinoma survived
shorter than patients with adenocarcinoma (hazard ratio 1.90, 95% CI: 1.29~2.79).
Patients with the first distant failure site being brain and bone had significantly worse
survival than those with lung to lung distant failure (hazard ratio: 2.04 and 1.80, 95%
CI: 1.25-3.35, and 1.16-2.77).
Conclusions: The survival was poor for patients of resected Stage I non-small cell
lung cancer after distant failure. Tumor size is the significant predictor for both disease-free and overall survival. |
| 關鍵詞 |
Stage I non-small cell lung cancer, distant failure, predictor, survival |
| 分類 |
Original Article |
|
