篇名 |
Disseminated intravascular coagulation in a stage IV colon cancer patient: report of a case and review of the literature |
作者 |
Li-Jen Kuo, Shuh-Yan Leu, Mei-Ching Liu, Chung-Ming Chen |
卷期/出版年月 |
36卷4期 (2003/8) |
頁次 |
188-192 |
摘要 |
Approximately 20% of patients with colorectal carcinoma are initially seen with stage IV of the disease. Here, we report a 45-year-old female patient with synchronous sigmoid colon cancer and multiple liver metastases. She underwent a palliative anterior resection and hepatic arterial infusion pump implantation. Left lower leg swelling developed four days after the operation and then shortness of breath was noted. Emergency lower extremity duplex ultrasound study proved the presence of left deep venous thrombosis. Chest helical computed tomography showed bilateral pulmonary arterial thromboembolism. Laboratory tests revealed a rapid decline in platelet count and fibrinogen level, and the presence of fibrin-degradation products in plasma. Under the impression of disseminated intravascular coagulation, systemic heparinization with low-molecular-weight heparin was employed Clinically speaking, the patient improved gradually with rise of p;atelet counts to the normal range several days later. |
關鍵詞 |
disseminated intravascular coagulation, colorectal cancer, deep vein thrombosis |
分類 |
Case Report |