| 篇名 |
Colon Perforation as Initial Manifestation of Post-Transplant Lymphoproliferative Disorder Following Kidney Transplant: Report of a Case |
| 作者 |
Tung-Cheng Chang, Meng-Kun Tsai, Wei-Chou Lin, Po-Huang Lee |
| 卷期/出版年月 |
41卷4期 (2008/8) |
| 頁次 |
158-162 |
| 摘要 |
A 39 year-old female suffered 2 days of abdominal pain approximately 11 months after cadaveric kidney transplantation. Emergent laparotomy revealed transverse colon ulceration with perforation and left ovarian tumor. Ulceration debridment, loop colostomy of the transverse colon, and left oophorectomy were carried out. Her post-operative course was uncomplicated. The pathological examination revealed polymorphic post-transplant lymphoproliferative disorder. Consequently immunosuppressants were reduced to half of the original dose and anti CD-20 antibody was given to this patient. Complete remission was noted after 4 doses of anti-CD-20 antibody. Colon perforation as the initial presentation of post-transplant lymphoproliferative disorder (PTLD) is unusual. However, early detection is necessary and aggressive investigation should be considered in suspicious cases with a high-risk of PTLD. |
| 關鍵詞 |
colon perforation, post-transplantation lymphoproliferative disorder, kidney transplantation |
| 分類 |
Case Report |
