| 篇名 | 
        Anal canal melanoma misdiagnosed and treated as prolapsed hemorrhoids in a male patient | 
      
      
        | 作者 | 
        T.A. Mala, R. Gupta, S.R. Ahmad, S.A. Malla, V.B. Gupta, I. Shah             | 
      
      
        | 卷期/出版年月 | 
        47卷2期 (2014/4) | 
      
      
        | 頁次 | 
        74-77 | 
      
      
        | 摘要 | 
        Malignant melanoma of the anal canal is a rare, but aggressive, tumor with a poor prognosis. It represents less than 1% of all melanomas and 4% of anorectal tumors. We are reporting this case because of its rarity in men and because, in this instance, the tumor was misdiagnosed as prolapsed thrombosed hemorrhoids and excised. Examination showed a visible exophytic irreducible growth measuring about 3×3 cm and protruding outside the anal verge and involving the anterior two-thirds of the circumference of the anal canal. A biopsy sample showed round to oval cells with prominent nucleoli and marked intracytoplasmic pigmentation.
A magnetic resonance imaging scan showed a tumor with nearly complete luminal
obstruction and liver metastasis. The patient received chemotherapy and radiotherapy, but the response was very poor and he died 2 months later. | 
      
      
        | 關鍵詞 | 
        anal canal melanoma;melanoma antigen HMB-45;protein S-100;thrombosed hemorrhoids | 
      
      
        | 分類 | 
        Case Report |