| 摘要 |
Primary squamous cell carcinoma of the prostate is extremely rare and accounts for 0.2 to 0.6% of all the cases of prostate cancers. The etiology is unclear. There are 1389 cases diagnosed as prostate cancer in our hospital from November, 1990 to June, 2007. Among these cases, only one case with squamous cell carcinoma of the prostate was encountered. The patient was 71 years old and his clinical symptoms included bladder outlet obstruction, hematuria, and dysuria. Transrectal ultrasound showed no hypoechoic lesions and the prostatic specific antigen (PSA) was normal. Digital rectal examination of the prostate revealed firm consistency, symmetric enlargement without nodularity. The diagnosis was made by needle biopsy. A review of the literature shows that primary squamous cell carcinoma of the prostate is extremely rare, and much more aggressive than adenocarcinoma of the prostate clinically with the average survival time of about 14 months after diagnosis. In various articles, radical surgery, radiotherapy and chemotherapy with mitroxantrone and cisplatin were mentioned but this kind of carcinoma responded poorly to these three modes of therapy. |
