中文 | ENG

第57卷 第6期 2024-11
Emerging robot-guided techniques in endodontic microsurgery

.........................

第57卷 第6期 2024-11
Management of subcapsular hematoma after living donor liver transplant

.........................

第57卷 第6期 2024-11
Urethral pseudodiverticulum with left-sided nonfunctioning kidney: Case report

.........................

第57卷 第6期 2024-11
Strategy to minimize surgical defect of dermatofi brosarcoma protuberans

.........................

第57卷 第6期 2024-11
Rapunzel syndrome—An uncommon disease with varied common presentations

.........................

第57卷 第6期 2024-11
Minimally invasive approaches to management of acute necrotizing pancreatitis

.........................

第57卷 第6期 2024-11
Innovative surgical technique: Addressing ethical concerns

.........................

第57卷 第6期 2024-11
Emergency surgery and HIV screening, clinical or universal scenarios?

.........................

第57卷 第6期 2024-11
High mortality rates associated with parainfl uenza virus, not metapneumovirus, infections in lung transplant recipients: A retrospective observation

.........................

第57卷 第6期 2024-11
Predatory clinical surgery journal, rescinding the decision to accept submitted article and unjustifi ed rejection and unprofessional conduct

.........................

第57卷 第6期 2024-11
Sacrifi cial of unilateral vertebral artery for fragment removal following vertebral artery injury by air rif le pellet gunshot: A case report

.........................

第57卷 第6期 2024-11
Evaluation of three-dimensional reconstruction technology in precision hepatectomy for primary liver cancer

.........................

第57卷 第6期 2024-11
Exploring the seasonal variation of anorectal disease: A comprehensive study

.........................

第57卷 第6期 2024-11
Efficacy of the minimal-invasive vacuum-assisted biopsy under direct visualization with ultrasound for impalpable breast lesions in Taiwanese female: A retrospective case-control study

.........................

第57卷 第6期 2024-11
Computed tomography on the 5th postoperative day helps distinguish grade C from grade B pancreatic fi stula after pancreaticoduodenectomy for periampullary cancer

.........................

第57卷 第6期 2024-11
Pressurized intraperitoneal aerosol chemotherapy (PIPAC): Why it will transform cancer surgery

.........................

第57卷 第5期 2024-9
Evaluating the pros and cons of anonymous commenting on PubPeer

.........................

第57卷 第5期 2024-9
Infected urachal cyst with urethral stricture disease presenting with intraperitoneal perforation of cyst and pyoperitoneum

.........................

第57卷 第5期 2024-9
COVID-19 vaccination and acute cholecystitis: A rare but important clinical problem

.........................

第57卷 第5期 2024-9
Hobnail-shaped primary prostatic urethral calculus due to urethral stricture disease

.........................
登入帳號才能閱讀全文
 
篇名 Surgical Resection Combined with Systemic Imatinib Therapy for the Treatment of Advanced Gastrointestinal Stromal Tumor
作者 Chi-Cheng Huang, Heng-Hui Lien, Ching-Shui Huang,Yuan-Chuan Sung
卷期/出版年月 37卷5期 (2004/10)
頁次 218-224
摘要 The results of surgical treatment of advanced gastrointestinal stromal tumor (GIST) are poor due to low resectability and high recurrence. This situation has been improved by the use of novel targeted molecular therapy with imatinib. For unresectable advanced GIST, the neo-adjuvant role of imatinib relies on cytoreduction and tumor shrinkage. The operability is increased and further definite surgery is facilitated. In cases with postoperative relapse, adjuvant imatinib therapy still provides the benefits of postponing tumor progression and enabling subsequent surgeries. We report two cases of advanced GISTs treated with surgery and imatinib. The first case was an inoperable advanced GIST with peritoneal sarcomatosis which became resectable after systemic imatinib therapy for 10 months. The second case had recurrent GIST after en bloc resection seven months earlier and resulted in stable disease status with continuous imatinib therapy. The timing, duration and dosage of imatinib remain inconclusive and demand further studies. Lifelong follow-up of advanced GISTs is mandatory.
關鍵詞 gastrointestinal stromal tumor, imatinib, surgery
分類 Case Report

台灣外科醫學會雜誌 © 2006 Taiwan Surgical Association All Rights Reserved
會 址:台北市南京東路五段 31 號 3 樓
電 話:(02) 2769-7845 傳 真:(02) 2746-7149 Email: journal@surgery.org.tw