篇名 |
Successful resection of huge hepatocellular carcinoma with inferior vena cava thrombus after downsizing by three-dimensional conformal radiation therapy and transarterial chemoembolization |
作者 |
Kuo-Chen Hung a,e, Pei-Min Hsieh a, Shyh-An Yeh b, Po-Lin Sun c,Li-Chien Huang d, Yaw-Sen Chen a,* |
卷期/出版年月 |
44卷4期 (2011/8) |
頁次 |
156-159 |
摘要 |
We report a successfully managed case of locally far-advanced hepatocellular
carcinoma (HCC) by preoperative downsizing by transarterial chemoembolization (TACE) and three-dimensional conformal radiation therapy (3D-CRT), with subsequent surgical resection. A 35-year-old man was referred to our hospital with right huge HCC in May, 2006. The laboratory data were normal except for elevated aspartate transaminase 100 U/L (0e38), alanine transaminase 54 U/L(0e44), and a-fetoprotein 32 ng/mL(1e8). A computed tomography scan of the liver revealed a 20-cm right side huge HCC with inferior vena cava tumor thrombus (IVC-TT) and a second 2-cm HCC in segment III. TACE was performed on the right HCC with 20 mg of doxorubicin (Adriamycin), mixed with 10 mL of lipiodol and gelfoam. 3D-CRT was followed by 60 Gy (3 Gy/fraction) over 4 weeks. The posttreatment computed tomography scan showed significant shrinkage of the right tumor and IVC-TT. The tumors with the concomitant IVC-TT were surgically removed 6 weeks later. |
關鍵詞 |
hepatic resection;hepatic vein tumor thrombus;hepatocellular carcinoma;inferior vena cava tumor thrombus; three-dimensional conformal radiation therapy;transarterial chemoembolization |
分類 |
Case Report |