|
|
第57卷 第2期 2024-3
Necrotizing fasciitis resulted from foreign body ingestion and intestinal perforation in an incisional hernia: Report of a case |
| ......................... |
|
第57卷 第2期 2024-3
Application of artificial intelligence in endodontic microsurgery |
| ......................... |
|
第57卷 第2期 2024-3
A rare case of cerebral metastasis of malignant peripheral nerve sheath tumor in a patient with neurofibromatosis type 1 |
| ......................... |
|
第57卷 第2期 2024-3
Ethic in commenting and clinical surgery journal publication: Emerging issue in the era of social media—A story from “Beall” to “Jaime” and independent researcher |
| ......................... |
|
第57卷 第2期 2024-3
Ophidascaris robertsi, the new emerging human parasite and neurosurgery |
| ......................... |
|
第57卷 第2期 2024-3
Tetanus toxoid IgG, usefulness in clinical surgery, and diagnostic property limitation |
| ......................... |
|
第57卷 第2期 2024-3
Deaths among surgeons while on duty: An important issue in surgery and occupational medicine that should not be disregarded |
| ......................... |
|
第57卷 第2期 2024-3
ChatGPT and its use in clinical surgery: A comment on its pro and con |
| ......................... |
|
第57卷 第2期 2024-3
Isolated spinal neurocysticercosis and pseudotumor cerebri: Tropical problem to be noted |
| ......................... |
|
第57卷 第2期 2024-3
Management of massive hemothorax resulting from traumatic diaphragm rupture with kidney avulsion injury by combined anterior thoracoabdominal approaches |
| ......................... |
|
第57卷 第2期 2024-3
Laparoscopic partial splenectomy for sclerosing angiomatoid nodular transformation: A case report and literature review |
| ......................... |
|
第57卷 第2期 2024-3
Using three-dimensional versus two-dimensional laparoscopy in sleeve gastrectomy: A case matched comparison |
| ......................... |
|
第57卷 第2期 2024-3
Effectiveness of placing prophylactic mesh with the Sugarbaker technique via laparoscopic abdominoperineal resection for rectal cancer: 1-year results |
| ......................... |
|
第57卷 第2期 2024-3
Nylon cable ties–assisted delay primary closure of fasciotomy wound in patients of forearm compartment syndrome |
| ......................... |
|
第57卷 第2期 2024-3
Prefabricated venous fl ap, an advanced free venous fl ap for distant transfer: An experimental rat study |
| ......................... |
|
第57卷 第1期 2024-1
Isolated lower leg monoplegia due to traumatic intraparenchymal hemorrhage |
| ......................... |
|
第57卷 第1期 2024-1
Reflections on the association between cholecystectomy, cholelithiasis, and colorectal cancer |
| ......................... |
|
第57卷 第1期 2024-1
Molluscum contagiosum, false positive, and incidence: Concern in surgery |
| ......................... |
|
第57卷 第1期 2024-1
New form of COVID-19 vaccine: A new advanced technology for fighting the remained problem |
| ......................... |
|
第57卷 第1期 2024-1
COVID-19 vaccination, acute appendicitis, interrelationship, and jointed probability: A concern |
| ......................... |
|
 |
| 篇名 |
The Effect of Platelet Gels on Lumbar Intertransverse Process Spinal Fusion in a Rabbit Model |
| 作者 |
Sung-Chun Lin, Shih-Peng Hsieh, Zhi-Hong Wen, Chieh-Hsien Tu, Chieng-Hsien Hung, Chi-Chieh Tang, Hsin-Pai Lee, Yen-Hsuan Jean |
| 卷期/出版年月 |
41卷1期 (2008/2) |
| 頁次 |
7-14 |
| 摘要 |
Objectives: Platelets contain many growth factors which enhance new bone
formation. Platelet-rich plasma however has little adhesive strength. This limits its application to some situations in orthopedic surgery such as fracture or spinal fusion. In this study, platelet gels were used in spinal fusion surgery to provide new bone formation and adhesive strength and prolong the effective period of time.
Methods: Sixteen adult rabbits received posterolateral intertransverse process
fusion at L5-L6 with the use of autogenous bone grafts. Rabbits were randomly
divided into experimental and control groups. Two groups of animals received
similar surgical procedures. The experimental group received an autogenous bone
graft mixed with platelet gels. The control group received an autogenous bone graft only. Posteroanterior radiographs of the spine were taken pre-operatively and then post-operatively every week for 6 weeks. Rabbits were euthanized at 6 weeks after surgery. The spinal fusion was assessed by radiographic analysis and by manual palpation at the level of arthrodesis and at the adjacent proximal and distal levels. Histopathological examination was performed by a biopsy of the bilateral fusion mass and evaluating fusion quality using the Emery grading scales.
Results: One rabbit died on the fifth day after the operation for an unknown
reason, while the other 15 rabbits (7 in the experimental group and 8 in the control group) survived until the 6th postoperative weeks. Each side of the spine was graded separately, and 11 of the 14 fusion masses (78.6%) in the experimental group and 10 of the 16 fusion masses (62.5%) in the control group had radiographic evidence of fusion. With gross manual palpation, 6 of the 7 motion segments (87.7%) in the experimental group versus 4 of the 8 motion segments (50%) in the control group were determined to have solid fusion. The difference was not statistically significant (p>0.05) for either the radiographic analysis or manual palpation. Histologically, however, the experimental group had a higher mean score (with a mean of 6.21 vs.5.06, p=0.03) and a higher fusion rate (85.7% vs. 31.3%, p=0.002), which were both
statistically significant.
Conclusion: Platelet gels can enhance new bone formation, thus increasing the
fusion rate of posterolateral spinal fusion in a rabbit model. |
| 關鍵詞 |
platelet gels, growth factor, spinal fusion, bone graft, arthrodesis |
| 分類 |
Original Article |
|
