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篇名 Speech Preservation by Neuronavigation with Functional MRI and Tractography in Tumor Involving the Broca’s Area: Report of a Case
作者 Tsung-Lang Chiu, Tsung-Hsien Wu, Ya-Jung Wang
卷期/出版年月 42卷4期 (2009/8)
頁次 214-218
摘要 To achieve maximal tumor excision and to save neuro-function are the supreme goal of neurosurgical practice. However, these two attempts are in conflict with each other in most circumstances and need careful estimate and balancing. With regard to this requirement, many advanced neuro-imaging procedures are focused on illumination of the active functional area of the cortex and the crucial fiber tract to implement in neuronavigation with anatomical imaging. Among the developing modalities, diffusion tensor imaging (DTI) and functional magnetic resonance imaging (fMRI) integrated with anatomical MRI have been most reliable in functional preservation. In this article, we illustrate a case of grade II astrocytoma involving Broca’s area and the internal capsule, treated under neuronavigation with imaging fusion of fMRI, DTI and anatomical MRI. The speech and motor functions were well preserved during the observation period of 12 months. Furthermore, there was no relapse of tumor shown by MRI evaluation. For verbal function preservation and maximal tumor excision, imaging fusion of fMRI and DTI in neuronavigation is of great benefit for a tumor involving Broca’s area.
關鍵詞 Broca’s area, arcuate fascicle, tractography, functional magnetic resonance imaging, neuronavigation, low grade astrocytoma
分類 Case Report

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