hyperparathyroidism
(2nd HPT) is noted due to hyperphosphatemia, a deficit of calcitriol
synthesis and hypocalcemia.
Symptoms of bone pain, skin itching, general weakness and insomnia with high
IPTH levels (> 650 pg/ml), hypercalcemia (> 10.1 mg/ml) and hyperphosphatemia (>
4.6 mg/dl) are indications for surgery. Total parathyroidectomy or subtotal
parathyridectomy is a cost effective procedure to treat symptomatic 2nd HPT. Total
parathryoidectomy plus subcutaneous autotransplantation is an easy method to
perform and it can avoid long-life hypoparathyroidism, which total
parathyroidectomy without autotransplantaion cannot. It is also easy to find and
remove the parathyroid tissue if recurrent hyperparathyroidism at the
transplantation site is found.
關鍵詞
secondary hyperparathyroidism, mechanism, total parathyroidectomy plus subcutaneous autotransplantation