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篇名 Perianal Lesion as the Leading Presentation of Langerhans Cell Histiocytosis: Report of a Case
作者 Chia-Chi Tsai, William Tzu-Liang Chen, Wen-Chien Ting,Hua-Che Chiang, Sheng-Chi Chang, Tung-Ying Chen, Ssu-Ming Huang
卷期/出版年月 42卷3期 (2009/6)
頁次 165-170
摘要 Langerhans cell histiocytosis is a proliferative hematological disease with pleomorphic characters. Here, we present a very unusual case of Langerhans cell histiocytosis in a young male patient without a specific previous medical history, who had a perianal lesion as the leading symptom. This 17-year-old patient presented with perianal erythematous nodules for two months, unresponsive to topicals. Langerhans cell histiocytosis was suggested by histopathological examination after excisional biopsy. Thorough investigations revealed additional involvement of the left posterior temporal region of the cranium ,and the left medial proximal tibia. However, these bone lesions caused no symptoms. Langerhans cell histiocytosis should always be included in the differential diagnosis list for patients with nonspecific perianal lesions. For any perianal mass in doubt, a simple biopsy examination is necessary.
關鍵詞 langerhans cell histiocytosis, immunohistology, perianal lesion, CD1a,S-100
分類 Case Report

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