篇名 |
Perianal Lesion as the Leading Presentation of Langerhans Cell Histiocytosis: Report of a Case |
作者 |
Chia-Chi Tsai, William Tzu-Liang Chen, Wen-Chien Ting,Hua-Che Chiang, Sheng-Chi Chang, Tung-Ying Chen, Ssu-Ming Huang |
卷期/出版年月 |
42卷3期 (2009/6) |
頁次 |
165-170 |
摘要 |
Langerhans cell histiocytosis is a proliferative hematological disease with
pleomorphic characters. Here, we present a very unusual case of Langerhans cell
histiocytosis in a young male patient without a specific previous medical history, who
had a perianal lesion as the leading symptom. This 17-year-old patient presented
with perianal erythematous nodules for two months, unresponsive to topicals.
Langerhans cell histiocytosis was suggested by histopathological examination after
excisional biopsy. Thorough investigations revealed additional involvement of the
left posterior temporal region of the cranium ,and the left medial proximal tibia.
However, these bone lesions caused no symptoms. Langerhans cell histiocytosis
should always be included in the differential diagnosis list for patients with
nonspecific perianal lesions. For any perianal mass in doubt, a simple biopsy
examination is necessary. |
關鍵詞 |
langerhans cell histiocytosis, immunohistology, perianal lesion, CD1a,S-100 |
分類 |
Case Report |