| 篇名 |
Medullary Thyroid Carcinoma |
| 作者 |
Yun-Jau Chang, Kuan-Tien Chen, Yao-Zen Chang, Kwang-Yi Liaw |
| 卷期/出版年月 |
28卷4期 (1995/8) |
| 頁次 |
285-290 |
| 摘要 |
Thyroid medullary carcinoma (MTC) is rare in the classification of thyroid cancer, with some association of multiple endocrine neoplasm (MEN) Ila. From January 1977 to December 1993, 30 patients with thyroid medullary carcinoma were treated in this Hospital and then analyzed retrospectively. Data were obtained from medical records. There were 12 men and 18 women, ranging in age from 15 to 78 years, with a mean age of 45.13 years. Lymph node metastasis was observed in 13 patients (46.4%), while distant metastsis was noted in 4 cases (lung metastasis in 3, liver metastasis in 1, case). Familial type were found in six patients (20%), three of whom are in the same family. Four cases of familial type were suspected to have MEN Ila syndrome (13.3%). Pheochromocytoma screening is especially important in these cases for the possibility of MEN Ila. Surgery is still the curative treatment for all MTC. However, pheochromocytoma has surgical priority.
Twenty-five patients received thyroidectomy with curative intent. Two
patients died 29 and 43 months, respectively, after operation. The five-year
survival rate was 86.6% (13/15). |
| 關鍵詞 |
medullary thyroid carcinoma, pheochromocytoma, multiple endocrine neoplasia, calcitonin, thyroidectomy, modified radical neck dissection |
| 分類 |
Original Article |
