| 篇名 |
Influence of Cardiopulmonary Bypass on Viscosity of Blood in Open Heart Surgery |
| 作者 |
Chir-Feei Wang, I-Shou Lin, Fang-Yue Lin, Che-Yen Chuang, Chun-Jean Lee |
| 卷期/出版年月 |
28卷4期 (1995/8) |
| 頁次 |
255-261 |
| 摘要 |
Patients undergoing open heart surgery depend upon hypothermia and cardiopulmonary bypass (CPB) to maintain organ perfusion during cardiac arrest. However, regional organ perfusion is greatly influenced by blood viscosity. In pract ice, hematocrit, plasma fibrinogen concentration and temperature are the most important factors regulating blood viscosity. Changes in blood viscosity during intracardiac operations with CPB and membrane oxygenators were studied in 20 adult patients at National Taiwan University Hospital. Blood samples were withdrawn to assess the rheologic properties by measuring whole blood and plasma viscosity with a Silenus cone-on-plate viscometer. The results showed neither uniform changes of whole blood viscosity among the patients during CPB, nor stat istically significant changes of plasma viscosity and blood viscosity with constantly adjusted hematocrit at 25%. It was concluded that, with the application of the new type of membrane oxygenator and improved CPB techniques, little change of blood viscosity can be found. |
| 關鍵詞 |
cardiopulmonary bypass, viscosity, open heart surgery |
| 分類 |
Original Article |
