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篇名 Squamous Cell Carcinoma of the Anal Canal: Radical and Palliative Treatments and Prognosis
作者 Ta-Cheng Wei, Po-Li Wei, Sen-Chang Yu, Shu-Chien Hsu
卷期/出版年月 29卷4期 (1996/8)
頁次 320-324
摘要 From January 1978 to December 1992, 20 patients with squamous cell carcinoma of the anal canal were treated here; 12 patients received radical treatment using a multimodality approach and eight patients, palliative treatment. Follow-up times of the patients ranged from 30 to 142 months, with a mean follow-up time of 87 months. For radical treatment, 8 (67%) of 12 patients had wide local excision initially. One patient retained anal continence and 11 patients required abdominoperineal resection. The overall five-year survival rate after wide local excision or abdominoperineal resection was 75%. There were no treatment-related deaths. Preoperative tumor size was the factor most significantly related to survival. Patients should be treated with chemoradiotherapy; if the treatment fails or the tumor recurs, surgical therapy is used to control local disease. Of those with palliative treatment, all 8 patients died of bilateral hepatic metastases between 3 to 35 months.
關鍵詞 squamous cell carcinoma, anal canal, chemoradiotherapy, surgery
分類 Original Article

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