篇名 |
Squamous Cell Carcinoma of the Anal Canal: Radical and Palliative Treatments and Prognosis |
作者 |
Ta-Cheng Wei, Po-Li Wei, Sen-Chang Yu, Shu-Chien Hsu |
卷期/出版年月 |
29卷4期 (1996/8) |
頁次 |
320-324 |
摘要 |
From January 1978 to December 1992, 20 patients with squamous cell carcinoma
of the anal canal were treated here; 12 patients received radical treatment using a multimodality approach and eight patients, palliative treatment. Follow-up times of the patients ranged from 30 to 142 months, with a mean follow-up time of 87 months. For radical treatment, 8 (67%) of 12 patients had wide local excision initially. One patient retained anal continence and 11 patients required abdominoperineal resection. The overall five-year survival rate after wide local excision or abdominoperineal resection was 75%. There were no treatment-related deaths. Preoperative tumor size was the factor most significantly related to survival. Patients should be treated with chemoradiotherapy; if the treatment fails or the tumor recurs, surgical therapy is used to control local disease. Of those with palliative treatment, all 8 patients died of bilateral hepatic metastases between 3 to 35 months. |
關鍵詞 |
squamous cell carcinoma, anal canal, chemoradiotherapy, surgery |
分類 |
Original Article |