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| 篇名 |
Male Breast Cancer: Single Medical Center Experience |
| 作者 |
Shih-Chung Wu, Shyr-Ming Sheen-Chen, Jin-Hsiang Yang, Yue-Wei Liu, Yaw-Sen Chen, Chih-Chi Wang, Chee-Cheng Yong, Kuen-Jo Hsieh, Shih-Ho Wang, Fong-Fu Chou |
| 卷期/出版年月 |
40卷5期 (2007/10) |
| 頁次 |
187-192 |
| 摘要 |
Objective: Male breast cancer is uncommon. It shares many similarities with breast cancer in women, but some differences exist. The purpose of this study is: 1) to investigate the experience of male breast cancers at Kaohsiung Chang Gung Memorial Hospital in the past 15 years, and 2) to review the literature with regard to male breast cancer.
Methods: We retrospectively analyzed the records of male breast cancer collected from 1992 to 2006 at Kaohsiung Chang Gung Memorial Hospital. All the details of patient demographics, tumor characteristics, including histopathological diagnosis, treatment undertaken and outcomes were collected.
Results: The mean age of the 24 male breast cancer patients was 62.4 years, and 10 of the patients had concurrent medical illness. Nineteen patients had a tumor larger than 2 cm. The majority of histopathologic diagnoses was infiltrating ductal carcinoma, and 15 out of the 19 patients (78.9%) had a hormone-receptor-positive disease. All patients underwent modified radical mastectomy, after which 10 patients received post-mastectomy irradiation therapy. Eighteen patients received adjuvant systemic therapy and achieved a 5-year survival rate of 81.3%, better than that for those who did not receive systemic therapy (40%). With a mean follow-up duration of 53.6 months, the breast cancer-specific 5-year survival rate was 71.4% and overall survival was 62.5%.
Conclusions: The mean age of men with breast cancer was older than that in the
female counterparts and consequently more medical co-morbidities were noted. Men should be made more aware of the disease to achieve an early diagnosis. In addition to surgery and radiation therapy, patients receiving adjuvant systemic therapy had more survival benefit than those who did not. |
| 關鍵詞 |
male, breast cancer |
| 分類 |
Original Articles |
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