| 摘要 |
The purposes of this study were to evaluate the efficacy and safety of packaged peripheral parenteral nutrition (PPPN), and to determine the effects of additional fat emulsion on postsurgical children. Two groups of patients, randomly assigned, received equivalent amounts of a glucose (8.9 g/kg/day) and amino acid (1.63 g/kg/day) formula which was mixed using PAREN-AID No. 2, TAITA No. 1 and PLAS-AMIN solutions. To supply a fat emulsion, which was not given to PPPN group patients (n= 16), 10% INTRA-LIPID (1 g/kg/day) was added to the solution for the other group (PPPN-F group) (n= 15). Peripheral total parenteral nutrition (TPN) was given for 6 days. Body measurements, including body weight, right triceps skin fold (TSF) and mid-arm circumference (MAC), were recorded. Blood and urine samples were collected on days O and 6 for determination of various bio-chemical values, including a complete blood cell count, levels of nutritional indicators, electrolytes, liver and renal function indicators, and nitrogen balance. After 6 days of TPN for both patient groups, no side effects were noted. Several parameters showed better outcomes in both groups of patients: total lymphocyte count and lymphocyte / white blood cell ratio
improved; serum prealbumin level increased; and a significantly better
nitrogen balance was observed. No adverse effect on liver function or renal function was detected. When comparing PPPN-F with PPPN group patients, the PPPN-F formula had a tendency to result in better values of TSF and MAC, and in improved postoperative serum prealbumin levels, although the changes had no significant difference. It is suggested that either PPPN or PPPN-F formula administration for 6 days is feasible, safe and adequately nourishing for recovery in postoperative pediatric patients who need to avoid any oral feeding for about one week after abdominal surgeries. |
