| 篇名 |
Posttransplantation Lymphoproliferative Disorder after Lung Transplantation |
| 作者 |
Jin-Shing Chen, Shi-Ping Luh, Yih-Leong Chang, Jang-Ming Lee, Chung-Jei Huang Yeun-Chung Chang,Yung-Chie Lee |
| 卷期/出版年月 |
31卷5期 (1998/10) |
| 頁次 |
314-319 |
| 摘要 |
Posttransplantation I ymphoproliferative disorder (PTLD) is an uncommon but
often fatal complication of solid organ transplantation. The incidence is relatively higher in pediatric patients or patients undergoing lung transplantation. The pathology of PTLD is a morphologically heterogeneous group of lymphoid proliferation of varying clonal composition, most commonly of B-cell origin, and the Epstein-Barr virus (EBV) has been implicated as a cofactor in most cases. Herein we report a 44-year-old woman who underwent right single lung
transplantation because of bronchiolitis obliterans associated with Sauropus
androgynus ingestion. Three nodules were noted at the grafted lung 3 months
after the operation. The CT-guided biopsies and serological studies revealed that these nodules were EBV-unrelated B-cell lymphoma. Despite treatment including antiviral agents, reduction of immunosuppression, as well as conventional chemotherapy, these nodules increased in size rapidly. This patient died of sepsis and respiratory failure 5 months after the transplantation. |
| 關鍵詞 |
posttransplantation lymphoproliferative disorder, lung transplan- tation, sauropus androgynus. |
| 分類 |
Case Reports |
