| 摘要 |
Solitary fibrous tumors of the pleura (SFTPs) are rare, slow-growing neoplasms that
are widely recognized as mesenchymal in origin. Grossly, most SFTP arise from the
visceral pleura in a pedunculated manner. Microscopically, they consist of spindle
fibroblast-like cells intimately intertwined with connective tissue in a disorderly
pattern. Immunohistochemically, the tumors are vimentin-positive and keratin-negative.
The expression of CD34, bcl-2, and CD99 can also be seen in most of them. We
report a giant (18 15 8 cm) SFTP in an 83-year-old man presenting with the
feeling of abdominal fullness and intermittent fever for more than 1 week. Abdominal
sonography showed a huge hyperechoic lesion above the right diaphragm. A chest
radiograph revealed opacity in the right lower lung field. A well-defined heterogeneous
mass in the right thorax, causing atelectasis of the right lower lobe and displacement
of the liver, was found on the contrast-enhanced computed tomography of
the chest. An ultrasound-guided needle biopsy demonstrated that spindle cells were
the dominant component of the neoplasm. Curative resection was performed and the
histologic and immunohistochemical studies confirmed an SFTP. The postoperative
recovery was uneventful and the patient has remained well on outpatient follow-up. |
