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第58卷 第3期 2025-5
Elevating the standards of scientific editing in clinical surgery: Learning from editorial and journal role models

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第58卷 第3期 2025-5
Improving online physician evaluations for surgeons using sentiment analysis and alternative perspectives

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第58卷 第3期 2025-5
Ensuring ethical and qualified authorship: The key to trustworthiness in clinical surgery journal

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第58卷 第3期 2025-5
Artificial intelligence for academic purpose in clinic surgery: ChatGPT, Turnitin, and false positive

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第58卷 第3期 2025-5
COVID-19, COVID-19 vaccination, risk of cardiac myxoma in view of clinical surgery

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第58卷 第3期 2025-5
Eggplant deformity in penile fracture

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第58卷 第3期 2025-5
Splenectomy for Klippel-Trenaunay syndrome: Systematic review and case series

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第58卷 第3期 2025-5
Comments on “Risk factors for spinal cord injury without radiographic abnormality in trauma cases at a single trauma center”

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第58卷 第3期 2025-5
Impact of fluorescence-guided surgery on splenic preservation: A case of splenic hydatidosis

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第58卷 第3期 2025-5
Adult pancreatoblastoma presentingwith obstructive jaundice: A case report and literature review

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第58卷 第3期 2025-5
Pilonidal disease management in young adults: A retrospective analysis of practices in a single tertiary center in Bahrain

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第58卷 第3期 2025-5
Long-term comparative outcomes in patients undergoing transcatheter aortic valve implantation with self-expanding valves versus balloon-expandable valves: A retrospective observational study

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第58卷 第3期 2025-5
Comparative study between the effectiveness of Amnion-CollaGee (Collagen-Gelatin-Elastin) as a biological product wound dressing and conventional dressing on the donor site of the split-thickness skin graft in animals model (rats)

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第58卷 第3期 2025-5
Enhancing mortality Probability Model II predictive accuracy with the lethal triad in intensive care unit trauma patients: A retrospective study

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第58卷 第3期 2025-5
Dr. Shao-Wei Chen's contribution to analysis of outcomes of patients undergoing cardiac surgery and aortic disease: Big data analytics

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第58卷 第2期 2025-3
Predatory publisher and low standard journal: An emerging problem in clinical surgery field

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第58卷 第2期 2025-3
Conflict of interest in clinical surgery: Contemporary concern in digital era

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第58卷 第2期 2025-3
Postpublication redecision and pitfalls of inadequate standards in scientific surgical journals: Important consideration in academic publication

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第58卷 第2期 2025-3
Spontaneous bilateral basal ganglia hemorrhage

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第58卷 第2期 2025-3
Academic characterization of the Formosan Journal of Surgery: A five-year bibliometric analysis

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篇名 The Ultrastructural Changes of The Common Bile Duct Folloing Reflux of Pancreatic Juice in A Canine Model
作者 Jer-Nan Lin, Chih-Chang Luo, Yat-Sen Ho
卷期/出版年月 32卷5期 (1999/10)
頁次 202-207
摘要 Pancreatic juice refluxing into the common bile duct (CBD) through an anomalous pancreaticobiliary ductal union has been regarded as one of the etiology in forming a choledochal cyst. However, the actual morphological changes of the CBD and hence the pathogenesis have not been demonstrated. A canine model in which continuous reflux of pancreatic juice into the bile duct was created by pancreaticocholedochostomy (PCS) were performed in 24 mongrel adult dogs. Twenty one dogs after PCS showed dilatation of CBD (diameter 7 to 15 mm, normal 2.2 +- 0.8mm) when they were sacrificed at 1, 2, 4, 8, 16 and 32 weeks respectively. The size of CBD reached maximally at 2 weeks after PCS, and remained the same at 32 weeks. The ultrastructure of the dilated CBD when examined under electron microscope showed mucosal sloughing, "splitting" of the intercellular junctional structures, basement membrance degeneration and rupture, submucosal vessel occlusion with ischemic necrosis, bile pigment deposition and fragmentation of the deep muscle layer. All these changes in the CBD suggested chemical destructive processes. We concluded that the bile-pancreatic juice mixture is harmful to the common bile duct and may cause limit degree of dilatation.
關鍵詞 choledochal cyst, abnormal pancreaticobiliary duct union, pancreatic juice reflux, electromicroscopic examination
分類 Original Articles

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