| 摘要 |
Localized Castleman's disease is a rare benign disorder which usually presents as an intrathoracic well-defined soft tissue mass without any symptoms. Surgical resection is mandatory for differential diagnosis and treatment. The purpose of this study was to present our surgical experiences in the management of localized Castleman's disease. From August 1988 through March 1999, five patients (4 men, 1 woman: age range, 18-56 years, mean age: 43 years) with final diagnosis of Castleman's disease were treted surgically at Taichung Veterans General Hospital. We reviewed the medical records of these five patients, including general data, clinical presentation, radiological findings, treatment and clinical follow-up. Abnormal mediastinal mass lesions were found on chest roentgenogram in all five patients. I four patients, mass lesions were found on chest roentgenogram in all five patients. I four patients, mass lesions demonstrated as well-defined, solitary soft tissue masses in the mediastinum which were homogenously enhanced after contrast infusion on computed tomography (CT) scan. Int remaining one patient, soft tissue mass infiltrated the bilateral brachiocephalic veins, superior vena cava nd ascending aorta. The four patients with well-defined soft tissue mass received conventional thoracotomy for tumor resection. The patient with infiltrating soft tissue mass underwent median sternotomy for debulking surgery. Adjuvant radiotherapy was administered to three patients, one for incomplete resection and the remaining two for uncertainty of complete resection. All of the patients were disease-free at the time of last follow-up. Generally, localized Castleman's disease can be cured by surgical resection. If complete resection is not possible, irradiation is a good choice as adjuvant therapy. |
