台灣外科醫學會雜誌

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篇名	Red blood cell distribution width ‑ A novel marker of inflammation and predictor of complications and outcomes among surgically managed patients
作者	Mukesh Khedar, Dharamanjai Kumar Sharma, Vijay Ola
卷期/出版年月	54卷4期 (2021/8)
頁次	130-134
摘要	Background: Red blood cell distribution width (RDW) is considered a marker of chronic inflammation and a predictor of poor outcome in seriously ill patients. This study is aimed to recognize RDW as a marker of inflammatory pathology and as a predictor of various postoperative complications and outcomes in terms of mortality. Materials and Methods: This was a retrospective study of all surgical patients retrieved from our prospectively collected database. RDW was studied as a marker of inflammatory pathology and as a predictor of various postoperative complications and outcomes in terms of mortality. Results: We analyzed 146 (99 males and 47 females) patients who were managed surgically for their presenting diseases. The mean age of presentation was 42.7 + 17.9 years. RDW was considered high when it was above 16%. RDW was observed to be high in 57 of 146 patients (39%). A significant correlation was found between elevated RDW and underlying inflammatory pathology (P < 0.001), development of postoperative complications (P < 0.001), and 30‑days mortality (P = 0.0023, Negative Predictive Value = 93.3%). High RDW and preexisting inflammatory pathology were found in strong association with postoperative complications. Conclusion: RDW was analyzed as a marker of inflammation and for its predictive accuracy of postoperative complications and mortality. We found statistically significant correlation between elevated RDW (>16%) and postoperative complications and 30‑day mortality. Strong correlation was also found between increased RDW and existing inflammatory pathology. RDW could be a useful indicator of chronic health state and practical addition to existing risk stratification strategy and decision‑making process.
關鍵詞	30‑day mortality, chronic inflammation, postoperative complications
分類	Original Article