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第58卷 第2期 2025-3
Predatory publisher and low standard journal: An emerging problem in clinical surgery field

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第58卷 第2期 2025-3
Conflict of interest in clinical surgery: Contemporary concern in digital era

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第58卷 第2期 2025-3
Postpublication redecision and pitfalls of inadequate standards in scientific surgical journals: Important consideration in academic publication

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第58卷 第2期 2025-3
Spontaneous bilateral basal ganglia hemorrhage

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第58卷 第2期 2025-3
Academic characterization of the Formosan Journal of Surgery: A five-year bibliometric analysis

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第58卷 第2期 2025-3
Supra-sternal reconstruction for a high-hanging fruit like right subclavian artery aneurysm

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第58卷 第2期 2025-3
Operations for choledochal cysts: A 25-year experience at a tertiary care center in India

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第58卷 第2期 2025-3
A case report: Can a titanised polypropylene mesh (TiMesh) obviate a dual mesh for sandwich technique for parastomal hernias?

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第58卷 第2期 2025-3
Recurrent gallstone ileus, a deadly encounter: A case report

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第58卷 第2期 2025-3
The changes in dietary intake and tolerance for Chinese food after bariatric surgery in Taiwan

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第58卷 第2期 2025-3
Diagnostic value of trans-recto-perineal ultrasound in perianal fistula—preoperative versus intraoperative findings: A comparative cross-section study

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第58卷 第2期 2025-3
Efficacy and safety of extended-release dinalbuphine sebacate for postoperative analgesia: A systematic review and meta-analysis

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第58卷 第2期 2025-3
Dynamic changes in segmented neutrophil-to-monocyte ratio in trauma patients with stress-induced hyperglycemia: A retrospective study

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第58卷 第1期 2025-1
Ensuring authorship qualification in clinical research articles: A focus on surgical therapy studies

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第58卷 第1期 2025-1
Estimated risk for transfusion of monkeypox contaminated perioperative blood transfusion: A call to action for stronger regulations and testing protocols

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第58卷 第1期 2025-1
Insights into traumatic and crisis surgery: Implications of data analysis in conflict zones

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第58卷 第1期 2025-1
Tongue peeling as an adverse reaction with use of micronized purified flavonoid: A case report

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第58卷 第1期 2025-1
Pilonidal sinus of scrotum: A rare clinical entity

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第58卷 第1期 2025-1
Incidental autopsy finding of retiform hemangioendothelioma of the spleen

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第58卷 第1期 2025-1
Retroperitoneal laparoscopy for hydronephrosis due to multiple fibroepithelial polyps: A case series

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篇名 Role of Protease Inhibitors in Acute Pancreatitis
作者 Han-Ming Chen, Miin-Fu Chen
卷期/出版年月 38卷3期 (2005/6)
頁次 101-109
摘要 The results of treatment with protease inhibitors for acute pancreatitis are conflicting. Although much work has focused on this special treatment modality, early investigations were not conclusive. The systemic inflammatory response that follows acute pancreatitis is a major concern in its pathophysiology. Among numerous candidate molecules, protease-protease inhibitor imbalance in the progression of acute pancreatitis is considered important in the trigger events within the human body. Recent work by the authors and other investigators has shown that small molecular-weight protease inhibitors are effective in the treatment of acute pancreatitis in the laboratory and in the clinical setting, especially in severe cases with organ dysfunctions. The new treatment protocols have opened a way to understanding the very aspects of the mechanism that underlies this complex disease. More work, however, is still needed for the complete elucidation of the effects protease inhibitors in acute pancreatitis.
關鍵詞 acute pancreatitis, gabexate mesilate, multiple organ dysfunction syndrome, protease inhibitor, sepsis, systemic inflammatory response syndrome
分類 Original Articles

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