篇名 |
Unusual Presentation of Appendiceal Adenocarcinoma:Report of a Case |
作者 |
Hsien Liu, Shyng-Shiou Yuan, Kai-Jen Lin,Chih-Kun Huang, Chao-Ming Hung, Yaw-Sen Chen |
卷期/出版年月 |
41卷5期 (2008/10) |
頁次 |
217-220 |
摘要 |
Sister Mary Joseph’s nodule, which can present as the first sign of internal
malignancies, is a rare form of cutaneous umbilical metastases and usually carries a
poor prognosis. A case of Sister Mary Joseph’s nodule caused by primary
appendiceal adenocarcinoma is presented. A 51-year-old female patient was with
umbilical discharge for one month. No other gastrointestinal symptoms was noted.
Physical examination revealed a hard, non-tender umbilical nodule with skin
discoloration and mucus-like discharge. Histopathologic examination of the
umbilical biopsy specimen revealed a mucin-producing, well-differentiated
adenocarcinoma. The primary lesion proved to be appendiceal adenocarcinoma with
invasion to right adnexa and uterus via further image study and exploratory
laparotomy. To the best of our knowledge, the case we present is the first reported
appendiceal adenocarcinoma with umbilical metastasis. The authors emphasize the
need for careful evaluation of any umbilical lesions and the importance of histologic
diagnosis when the origin of the diseases is undetermined. |
關鍵詞 |
Sister Mary Joseph nodule, umbilical metastasis, appendiceal neoplasm |
分類 |
Case Report |