| 摘要 |
There are many etological factors associated with bacterial translocation. Patients with colorectal cancer are frequently associated with a few of these factors such as malnutrition, immunosuppression, and obstruction. This study was designed to determine whether patients with colorectal cancer have high incidence of bacterial translocation. 286 patients operated for colorectal cancer from January 1995 to August 1998 were entered in this study. There were 141 males and 145 females. Ages ranged from 13 to 92 years old (average 62.34 years old). The distribution of tumor sites was listed as follows: 164 in the rectum, 55 in the sigmoid, 12 descending colon cancer, 20 transverse colon cancer, 36 ascending colon cancer, 20 transverse colon cancer, 36 ascending colon cancer, and 4 in the cecum. Thirty five patients had acute colonic obstruction. Culture of the mesenteric lymph node was taken prior to the dissection of the colon. There were nine (3.15%) positive cultures Positive culture occurred in two patients with obstruction, higher than non-obstructive patients (5.71% vs 2.79%). Although bacterial translocation is not high in patients with colorectal cancer, higher incidence of translocation to mesenteric lymph node in obstructive group may warrant administration of anibiotics longer than just for prophylaxis. |
